Item Introduction
Natural Postbiotics
The strain with targeted functionality directly ferments natural materials as a
substrate, and when consumed as a heat-killed formulation afterward, it
provides health benefits.
Contains heat-killed bacteria, microorganisms, and natural metabolic
components
Limitations of Existing Materials
- Lactic acid bacteria:
- Difficult quality control due to live bacteria, resulting in safety and stability limitations
- Natural extracts:
- Poor digestibility due to high molecular weight and low bioavailability
- ① Mental health improvement
- ② Anti-obesity
- ③ Anti-hypertension
- ④ Anti-diabetes
- ⑤ Anti-inflammatory
- ⑥ Others
- ① AI Big Data
- ② Database Utilization
- ① Time
- ② Temperature
- ① UHPLC
- ② Q-TOF
- ③ AI
- ④ DB
- ① Efficacy
- ② Marker/Functional Components
- ③ Microbiome
- ① Evaluation of marker/functional components and quality standards
- ② Efficacy Verification
Core Technology
Gut Health Regulation
(Increasing beneficial bacteria and reducing harmful bacteria)
Metabolite Regulation
(Beneficial bacteria produce beneficial metabolites)
Regulation via Gut-Organ Axis
(e.g., Gut-Brain axis, Gut-Muscle axis, etc.)
Target functional expression
via beneficial metabolites
Differentiated Technology
Existing postbiotics include only heat-killed lactic acid bacteria and their metabolites
Our natural postbiotics
contain not only heat-killed lactic acid bacteria and their metabolites
but also additional low-molecular functional compounds derived from the raw material
Raw material-derived
functional components [High Molecular]
Raw material-derived
functional components [Low Molecular]
- Effect 1 : Increased metabolites
- Effect 2 : Increased marker/functional components
- Effect 3 : Enhanced functionality (efficacy)
- Effect 4 : Significantly improved digestion and absorption
- Effect 5 : Improved gut microbiota through beneficial bacteria and their metabolites
Why Natural Postbiotics?
1 Enhanced Metabolites and Efficacy
- Increase in metabolites and marker/functional components
- Enhanced functionality (efficacy)
- Significantly improved digestion and absorption
2 Excellent Gut Health Improvement
- Gut microbiota improvement
- Beneficial metabolite production
- Short-Chain Fatty Acid (SCFA)* production
Related Patents
Patent Applications
| Application No. | Title |
|---|---|
| 10-2024-0035890 | Antioxidant or anti-obesity composition containing fermented onion extract (postbiotics) as an active ingredient |
| 10-2024-0059622 | Composition for improving obesity or cognitive function containing fermented hemp seed extract |
| 10-2024-0070535 | Probiotics and feed additive composition containing novel Pediococcus acidilactici and Saccharomyces boulardii strains for improving egg productivity and quality of spent hens |
| 10-2025-0051334 | Composition for preventing, improving, or treating arthritis containing fermented green tea postbiotics as an active ingredient |
| 10-2025-0056802 | Composition for preventing, improving, or treating rheumatoid arthritis through gut microbiota balance containing fermented hemp seed extract as an active ingredient |
| 10-2025-0059396 | Composition for improving obesity, enhancing cognitive function and memory, and preventing Alzheimer's disease containing fermented hemp seed extract as an active ingredient |
| 10-2025-0061676 | Anti-obesity composition containing fermented chicory root extract as an active ingredient |
| 10-2025-0094404 | Antibacterial, anti-inflammatory, or antioxidant composition containing fermented Codonopsis lanceolata extract or its postbiotics as an active ingredient |
| 10-2021-0181949 | Novel Limosilactobacillus strain and food composition for improving antioxidant or anti-stress function containing fermented rice extract using the same |
| 10-2025-0179325 | Extracellular polysaccharide derived from Leuconostoc mesenteroides OHVJ:2 showing immunomodulatory activity |
| 10-2025-0179326 | Polyphenol capsule derived from fermented perilla leaf or its postbiotics using extracellular polysaccharide derived from Limosilactobacillus reuteri KCTC 15843BP as an active ingredient for preventing colorectal cancer |
Registered Patents
| Registration No. | Title |
|---|---|
| 10-2647158-00-00 | Novel Pediococcus acidilactici strain and various uses of fermented soybean products using the same |
| 10-2149139-00-00 | Lactic acid bacteria fermentation products of garlic and Cirsium setidens, manufacturing method and uses thereof |
| 10-2178556-00-00 | Prebiotic composition for improving gut microbiota containing garlic peel extract and functional food containing the same |
International Applications (PCT)
| International Application No. | Title |
|---|---|
| PCT/KR2023/007343 | Novel Limosilactobacillus strain and food composition for improving antioxidant or anti-stress function containing fermented rice extract using the same |
| PCT/KR2025/006129 | Composition for improving obesity, enhancing cognitive function and memory, and preventing Alzheimer's disease containing fermented hemp seed extract as an active ingredient |
| PCT/KR2025/007651 | Composition for preventing, improving, or treating rheumatoid arthritis through gut microbiota improvement containing fermented hemp seed extract (postbiotics) as an active ingredient |
Applications
